Drugs for alcohol dependence

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Acamprosate for alcohol dependence.

BACKGROUND Alcohol dependence is among the main leading health risk factors in most developed and developing countries. Therapeutic success of psychosocial programs for relapse prevention is moderate, but could potentially be increased by an adjuvant treatment with the glutamate antagonist acamprosate. OBJECTIVES To determine the effectiveness and tolerability of acamprosate in comparison to ...

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Pharmacotherapy for alcohol dependence.

Alcoholism is a major public health problem that is detrimental to the affected individuals as well as to society as a whole. It has been popular belief that alcohol dependence can be controlled through will power, skill building, and support. Therefore, psychosocial therapies have historically been the most utilized treatments for alcohol use disorders.(1).

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Topiramate for alcohol dependence.

OBJECTIVE To evaluate the evidence for the use of topiramate for alcohol dependence. DATA SOURCES MEDLINE (1966-June 2008) and Cochrane Database (2008, Issue 1) searches were conducted using the search terms alcohol dependence and topiramate. Bibliographies of selected articles were examined for additional data sources. STUDY SELECTION AND DATA EXTRACTION English-language, randomized, contr...

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New pharmacotherapies for alcohol dependence.

Two pharmacotherapies recently introduced in Australia, acamprosate and naltrexone, provide a major advance in the treatment of severe alcohol dependence, a common condition leading to a considerable burden of illness and major costs to the community. Acamprosate and naltrexone reduce alcohol intake, and increase the likelihood and prolong the duration of abstinence (Level I evidence). Compared...

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ژورنال

عنوان ژورنال: Medicine

سال: 2020

ISSN: 1357-3039

DOI: 10.1016/j.mpmed.2020.09.004